Hey there, I started getting this problem with Kicad 5.1.0. Installed 5.1.4 and it is still happening.
Whenever I click Eeschema it simply doesn’t open.
In my windows toolbar an eeschema window is created, but it has a blank (completely white) thumbnail and clicking on it doesn’t open anything.
Run as administrator doesn’t work.
If that solves it then make a bug report attaching the backup of the settings folder and the new working folder.
Generally: sounds like a bug so you might as well make a report. The more information you can collect the better the chances your problem can be somehow fixed.