My 2 cents.. your M.2 connector misses Pin 1 mark.
And you should get rid of the silkscreen print for U2 as it's not needed and due to positional errors looks bad.
Oh, and when you do mousebites (did you make them or did OSHpark make them?) I'd make sure they sit deeper so you don't have those spikey things left sticking out but being recessed to the overall edge where they can't do harm.
The copper plane around those pads doesn't look exposed to me? Those are thermal spokes..
R4 on the other hand has got a track going by too close for those soldermask clearances and positional errors and the track get's uncovered partly:
Also the routing of that connection between pad 72 & 74 of the M.2 connector looks a bit odd to me (as pad 72 is extended it must be connected to something like the copper pour there?):
Overall I would say the soldermask clearance setting is a bit on the high side for the positional error being shown here and could have been dialed down somewhat (0.05 mm instead of 0.1 mm).