I think it should be possible. I use 0603 resistors. Under 0603 I can go with only one track while you can go with plenty of tracks under your elements allowing to unravel the connections.
I spend about 80% of time on searching the element placement simplifying me the tracks that I have to then make.
Here is my example of 2 layer PCB with whole bottom being GND:
In VCC connection I used three 0R resistors to avoid having to go with tracks on bottom. The key conception was to go with VCC under the main microcontroller and spread it out radially from there to all other ICs.